TitleSkill learning and repetition priming in Alzheimer's disease.
Publication TypeJournal Article
Year of Publication1992
AuthorsGrober, E, Ausubel, R, Sliwinski, M, Gordon, B
Date Published1992 Oct
KeywordsAged, Alzheimer Disease, Attention, Awareness, Dominance, Cerebral, Humans, Mental Recall, Neuropsychological Tests, Orientation, Pattern Recognition, Visual, Practice, Psychological, Reaction Time, Reading, Retention, Psychology

<p>While perceptual-motor learning occurs normally in Alzheimer's disease (AD) patients, their ability to acquire the skill of reading transformed text has not been well delineated. AD patients and matched controls were timed as they read two blocks of words presented in mirror image. Control subjects displayed both skill learning and repetition priming, whereas AD patients displayed only repetition priming. Skill learning in AD patients was associated with their ability to complete verbal analogies. They displayed the expected impairment in recognition for the words from the mirror reading task. The failure of AD patients to acquire the mirror reading skill can be understood through a task analysis and may reflect an underlying deficit in abstract reasoning that precludes the development of appropriate pattern analyzing strategies needed to transform rotated text.</p>

Alternate JournalNeuropsychologia
PubMed ID1436432
Grant ListAGO-3949 / AG / NIA NIH HHS / United States