TitleThe providing resources to enhance African American patients' readiness to make decisions about kidney disease (PREPARED) study: protocol of a randomized controlled trial.
Publication TypeJournal Article
Year of Publication2012
AuthorsEphraim, PL, Powe, NR, Rabb, H, Ameling, J, Auguste, P, Lewis-Boyer, LP, Greer, RC, Crews, DC, Purnell, TS, Jaar, BG, DePasquale, N, L Boulware, E
JournalBMC Nephrol
Date Published2012 Oct 12
KeywordsAttitude to Health, Black or African American, Health Care Rationing, Humans, Informed Consent, Kidney Transplantation, Living Donors, Patient Education as Topic, Patient Participation, Research Design, United States

<p><b>BACKGROUND: </b>Living related kidney transplantation (LRT) is underutilized, particularly among African Americans. The effectiveness of informational and financial interventions to enhance informed decision-making among African Americans with end stage renal disease (ESRD) and improve rates of LRT is unknown.</p><p><b>METHODS/DESIGN: </b>We report the protocol of the Providing Resources to Enhance African American Patients' Readiness to Make Decisions about Kidney Disease (PREPARED) Study, a two-phase study utilizing qualitative and quantitative research methods to design and test the effectiveness of informational (focused on shared decision-making) and financial interventions to overcome barriers to pursuit of LRT among African American patients and their families. Study Phase I involved the evidence-based development of informational materials as well as a financial intervention to enhance African American patients' and families' proficiency in shared decision-making regarding LRT. In Study Phase 2, we are currently conducting a randomized controlled trial in which patients with new-onset ESRD receive 1) usual dialysis care by their nephrologists, 2) the informational intervention (educational video and handbook), or 3) the informational intervention in addition to the option of participating in a live kidney donor financial assistance program. The primary outcome of the randomized controlled trial will include patients' self-reported rates of consideration of LRT (including family discussions of LRT, patient-physician discussions of LRT, and identification of a LRT donor).</p><p><b>DISCUSSION: </b>Results from the PREPARED study will provide needed evidence on ways to enhance the decision to pursue LRT among African American patients with ESRD.</p>

Alternate JournalBMC Nephrol
PubMed ID23057616
PubMed Central IDPMC3489555
Grant ListF31 DK084840 / DK / NIDDK NIH HHS / United States
K23 DK094975 / DK / NIDDK NIH HHS / United States
R01DK079682 / DK / NIDDK NIH HHS / United States