TitleModeling cognitive trajectories within longitudinal studies: a focus on older adults.
Publication TypeJournal Article
Year of Publication2010
AuthorsSteinerman, JR, Hall, CB, Sliwinski, MJ, Lipton, RB
JournalJ Am Geriatr Soc
Volume58 Suppl 2
PaginationS313-8
Date Published2010 Oct
ISSN1532-5415
KeywordsAged, Aging, Cognition, Cognition Disorders, Geriatric Assessment, Humans, Longitudinal Studies, Models, Theoretical
Abstract

<p>The natural history of life span cognitive performance and its late-life determinants have been studied from an array of perspectives. Significant insights come from psychological disciplines, including cognitive, developmental, and neuropsychology, as well as from medical specialties, such as geriatrics, neurology, psychiatry, neuroradiology, and neuropathology, that contribute to the growing interdisciplinary scientific field: cognitive neuroscience of aging. This survey of longitudinal studies of aging suggests that disease-oriented investigations commonly do not adequately consider normative cognitive changes, whereas developmental studies do not sufficiently measure and model nonnormative cognitive aging. This article argues for an integrative perspective that considers both of these influences on cognitive trajectories and presents a series of methodological concerns that have not been addressed comprehensively. Interdisciplinary methods from longitudinal observational studies should be leveraged to enable translational interventions to promote brain longevity.</p>

DOI10.1111/j.1532-5415.2010.02982.x
Alternate JournalJ Am Geriatr Soc
PubMed ID21029060
PubMed Central IDPMC3057764
Grant ListP01 AG003949 / AG / NIA NIH HHS / United States
AG003949 / AG / NIA NIH HHS / United States