TitleImpact of close family members on older adults' early response to depression treatment.
Publication TypeJournal Article
Year of Publication2008
AuthorsMartire, LM, Schulz, R, Reynolds, CF, Morse, JQ, Butters, MA, Hinrichsen, GA
JournalPsychol Aging
Volume23
Issue2
Pagination447-52
Date Published2008 Jun
ISSN0882-7974
KeywordsAged, Aged, 80 and over, Antidepressive Agents, Second-Generation, Attitude to Health, Caregivers, Citalopram, Combined Modality Therapy, Cost of Illness, Depressive Disorder, Major, Female, Humans, Male, Middle Aged, Personality Inventory, Psychotherapy, Social Support, Treatment Outcome
Abstract

<p>This study of 130 depressed older adults and their spouses or adult children examined the impact of caregiver burden specific to patients' depressive symptoms on patients' response to antidepressant treatment. Primary care patients completed medical, psychiatric, and neuropsychological assessments prior to treatment, and interviews were conducted with their identified family member. As hypothesized, caregivers' depression-specific burden predicted greater depression severity for the patient at the 6th week of treatment after accounting for patients' pretreatment characteristics, caregivers' depressive symptoms, and caregivers' relationship satisfaction. Future research may identify family attitudes and behaviors that stem from burden and compromise older adults' ability to recover from depression.</p>

DOI10.1037/0882-7974.23.2.447
Alternate JournalPsychol Aging
PubMed ID18573018
PubMed Central IDPMC2788400
Grant ListR01 AG015321 / AG / NIA NIH HHS / United States
R37 MH043832 / MH / NIMH NIH HHS / United States
R37 NG43832 / / PHS HHS / United States
R01 MH037869-25 / MH / NIMH NIH HHS / United States
R01 NR008272 / NR / NINR NIH HHS / United States
R01 AG015321-10 / AG / NIA NIH HHS / United States
P30 MH071944 / MH / NIMH NIH HHS / United States
R01 MH043832-19 / MH / NIMH NIH HHS / United States
K01 MH065547 / MH / NIMH NIH HHS / United States
R01 MH37869 / MH / NIMH NIH HHS / United States
R01 MH072947 / MH / NIMH NIH HHS / United States
K01 MH065547-05 / MH / NIMH NIH HHS / United States
R01 MH072947-05 / MH / NIMH NIH HHS / United States
R01 MH037869 / MH / NIMH NIH HHS / United States
P30 MH071944-05 / MH / NIMH NIH HHS / United States
R01 NR008272-05 / NR / NINR NIH HHS / United States