TitleFrontiers in the use of biomarkers of health in research on stress and aging.
Publication TypeJournal Article
Year of Publication2010
AuthorsPiazza, JR, Almeida, DM, Dmitrieva, NO, Klein, LC
JournalJ Gerontol B Psychol Sci Soc Sci
Volume65
Issue5
Pagination513-25
Date Published2010 Sep
ISSN1758-5368
KeywordsAdrenal Medulla, Aging, Biomarkers, Humans, Hypothalamo-Hypophyseal System, Immune System, Life Change Events, Stress, Physiological, Stress, Psychological, Sympathetic Nervous System
Abstract

<p>Assessment of biomarkers that reflect objective indicators of physiological processes has become increasingly popular in psychological research on stress and aging. The current article reviews biomarkers of the neuroendocrine and immune systems, including issues related to measurement and normative age-related changes. We also discuss how exposure to stressors can provoke changes in these biomarkers and propose that stressful experiences may accelerate age-related declines in these systems. We recommend that future research examining physical health and aging incorporate dynamic and multivariate methods for assessing links between stressors and biomarkers.</p>

DOI10.1093/geronb/gbq049
Alternate JournalJ Gerontol B Psychol Sci Soc Sci
PubMed ID20647348
PubMed Central IDPMC2920946
Grant ListP01 AG020166 / AG / NIA NIH HHS / United States
R01AG019239 / AG / NIA NIH HHS / United States