TitleThe association of visual memory with hippocampal volume.
Publication TypeJournal Article
Year of Publication2017
AuthorsZammit, AR, Ezzati, A, Katz, MJ, Zimmerman, ME, Lipton, ML, Sliwinski, MJ, Lipton, RB
JournalPLoS One
Date Published2017
KeywordsAged, Aged, 80 and over, Aging, Cross-Sectional Studies, Female, Hippocampus, Humans, Magnetic Resonance Imaging, Male, Mental Recall, Neuropsychological Tests, Organ Size, Pattern Recognition, Visual

<p><b>BACKGROUND: </b>In this study we investigated the role of hippocampal volume (HV) in visual memory.</p><p><b>METHODS: </b>Participants were a subsample of older adults (> = 70 years) from the Einstein Aging Study. Visual performance was measured using the Complex Figure (CF) copy and delayed recall tasks from the Repeatable Battery for the Assessment of Neuropsychological Status. Linear regressions were fitted to study associations between HV and visual tasks.</p><p><b>RESULTS: </b>Participants' (n = 113, mean age = 78.9 years) average scores on the CF copy and delayed recall were 17.4 and 11.6, respectively. CF delayed recall was associated with total (β = .031, p = 0.001) and left (β = 0.031, p = 0.001) and right HVs (β = 0.24, p = 0.012). CF delayed recall remained significantly associated with left HV even after we also included right HV (β = 0.27, p = 0.025) and the CF copy task (β = 0.30, p = 0.009) in the model. CF copy did not show any significant associations with HV.</p><p><b>CONCLUSION: </b>Our results suggest that left HV contributes in retrieval of visual memory in older adults.</p>

Alternate JournalPLoS One
PubMed ID29117260
PubMed Central IDPMC5678713
Grant ListK01 AG054700 / AG / NIA NIH HHS / United States
P01 AG003949 / AG / NIA NIH HHS / United States
UL1 TR001073 / TR / NCATS NIH HHS / United States