Title | The association of late-life depression and anxiety with physical disability: a review of the literature and prospectus for future research. |
Publication Type | Journal Article |
Year of Publication | 2001 |
Authors | Lenze, EJ, Rogers, JC, Martire, LM, Mulsant, BH, Rollman, BL, Dew, MA, Schulz, R, Reynolds, CF |
Journal | Am J Geriatr Psychiatry |
Volume | 9 |
Issue | 2 |
Pagination | 113-35 |
Date Published | 2001 Spring |
ISSN | 1064-7481 |
Keywords | Activities of Daily Living, Aged, Aged, 80 and over, Anxiety, Depression, Frail Elderly, Humans, Middle Aged, Persons with Disabilities, Research, Risk Factors |
Abstract | <p>Depression and anxiety disorders are associated with excess disability. The authors searched the recent geriatric literature for studies associating late-life depression or anxiety with physical disability. Studies showed depression in old age to be an independent risk factor for disability; similarly, disability was found to be a risk factor for depression. Anxiety in late life was also found to be a risk factor for disability, although not necessarily independently of depression. Increased disability due to depression is only partly explained by differences in socioeconomic measures, medical conditions, and cognition. Physical disability improves with treatment for depression; comparable studies have not been done for anxiety. The authors discuss how these findings inform current concepts of physical disability and discuss the implications for future intervention studies of late-life depression and anxiety disorders.</p> |
Alternate Journal | Am J Geriatr Psychiatry |
PubMed ID | 11316616 |
Grant List | K01 MH01613 / MH / NIMH NIH HHS / United States K05 MH00295 / MH / NIMH NIH HHS / United States P30 MH 52247 / MH / NIMH NIH HHS / United States R01 MH37869 / MH / NIMH NIH HHS / United States R01 MH59318 / MH / NIMH NIH HHS / United States R37MH43832 / MH / NIMH NIH HHS / United States T32 MH19986 / MH / NIMH NIH HHS / United States |