Epigenetic Age Acceleration and Brain Health (EPIGENETICS)

This NIH-funded project gathers data from nearly 3000 individuals across four international cohorts to examine the impact of child maltreatment on epigenetic age acceleration, a cross-tissue index of the biological aging of cells that differs from chronological age. This study examines epigenetic age acceleration and its relation to mid-life cognitive function. Results will inform precision-based efforts at preventing, delaying, or reversing the onset of various cognitive aging outcomes across different points of the lifespan.